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Search Results for " antipsychotic activity "

20

Compounds

Cat No. Product Name Synonyms Targets
T25487 Haloperidol decanoate KD 16,KD-136,KD 136,Neoperidole,Haldol Others
Haloperidol decanoate (KD 16) is a typical antipsychotic agent utilized as maintenance treatment for schizophrenia and mood disorders formulated as an ester for intramuscular injection.
T5858 Sertindole Lu 23-174 Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Autophagy
Sertindole (Lu 23-174) is an atypical antipsychotic that binds to dopamine D2 receptors and the serotonin (5-HT) receptor subtypes 5-HT1D, 5-HT2A, and 5-HT2C (Kds = 2.7, 20, 0.14, and 6 nM, respectively)
T13620 Clothixamide Clotixamide Others
Clothixamide(Clotixamide) is a thioxanthene derivative with antipsychotic activity.
T28267 ORM-10921 ORM10921,ORM 10921 Adrenergic Receptor
ORM-10921 is an α2C-adrenoceptor antagonist that has shown antipsychotic and antidepressant activity in animal studies.
T28231 Olanzapine N-Oxide Others
Olanzapine N-Oxide is a metabolite of Olanzapine which shows antipsychotic activity.
T10989 Dehydroaripiprazole OPC-14857,DM-14857 5-HT Receptor
Dehydroaripiprazole (DM-14857) is the active metabolite of aripiprazole. Aripiprazole is an antipsychotic drug, which is metabolized by CYP3A4 and CYP2D6 and mainly forms dehydroaripiprazole. Dehydroaripiprazole has anti...
T20797 NE-100 hydrochloride NE100 Hydrochloride,NE 100 HCl,NE 100 Hydrochloride,NE-100 Hydrochloride,NE-100 HCl Sigma receptor
NE-100 hydrochloride (NE-100 HCl) is a potent and selective antagonist of σ1 (IC50 = 4.16 nM) with antipsychotic activity. NE100 HCl also suppresses ER stress-induced hippocampal cell death.
T68047 Clopipazan Others
Clopipazan is an antipsychotic and antidepressant compound.Clopipazan has sedative and anxiolytic activity, possibly due to selective GABergic blockade of certain interneurons.
T1740 BD-1047 dihydrobromide BD1047.2HBr Sigma receptor
BD-1047 dihydrobromide (BD1047.2HBr) , a selective functional antagonist of sigma receptors, has antipsychotic activity in animal models predictive of efficacy in schizophrenia.
T0031L Ziprasidone hydrochloride CP-88059 hydrochloride,CP-88059,Ziprasidone HCl Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Norepinephrine , Histamine Receptor
Ziprasidone hydrochloride (CP-88059 hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity.
T39211 PD 144418 oxalate Sigma receptor
PD 144418 oxalate is a highly potent and selective sigma 1 (σ1) receptor ligand, displaying a Ki value of 0.08 nM for σ1 and 1377 nM for σ2. It exhibits negligible affinity for other receptors, ion channels, and enzymes....
T0766 Promazine hydrochloride Romtiazin hydrochloride,Sinophenin hydrochloride Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR
Promazine hydrochloride (Romtiazin hydrochloride) is a phenothiazine with actions similar to CHLORPROMAZINE but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as ...
T23854 Carbidine Carbidine dihydrochloride,Karbidin,Carbidin,Karbidine Others
Carbidine (Carbidin) is a derivative of gamma-carboline, an atypical antipsychotic drug. It reduces the inhibitory effect of DA on the 3H-DA release from synaptosomes of the nucleus accumbens septi and on the activity of...
T24885L Tiaspirone hydrochloride BMY-13859 hydrochloride,Tiaspirone hydrochloride(87691-91-6 Free base) Dopamine Receptor , 5-HT Receptor
Tiaspirone hydrochloride (BMY-13859 hydrochloride) exhibits antipsychotic activity. Tiaspirone hydrochloride influences the electrophysiological activity of dopaminergic neurons in the substantia nigra zona compacta (A9 ...
T0031 Ziprasidone hydrochloride monohydrate CP 88059 Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Norepinephrine , Histamine Receptor
Ziprasidone hydrochloride monohydrate (CP 88059) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of the antipsychotic activity.
T21855 AMI-193 Espiramida,Spiramide Dopamine Receptor , 5-HT Receptor
AMI-193 (Spiramide) is an effective and selective antagonist of 5-HT2 and D2 receptor with Kis of 2, 3, 50, 2530, and 4300 nM for 5-HT2, D2 Receptor, 5-HT1A, D1 Receptor, and 5-HT1C Receptor. AMI-193 shows antipsychotic ...
T0031L2 Ziprasidone Geodon,Zeldox,CP-88059 Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Norepinephrine , Histamine Receptor
Ziprasidone (Geodon) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity.
T23318L SB 258585 5-HT Receptor
SB 258585 is a selective 5-HT6 receptor antagonist.SB 258585 has a high affinity for individual receptor populations in cell lines with human recombinant 5-HT6 receptors.SB 258585 can be used to label both recombinant an...
T0455 Clozapine HF 1854,LX 100-129 Dopamine Receptor , Adrenergic Receptor , AChR
Clozapine (HF 1854) is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a...
T21368 Thioproperazine Megeptil,Sulfenazin,Cephalmin,Majeptyl,Vontil,Mazeptyl
Thioproperazine is a drug with the activity of antipsychotic.

Compounds

Haloperidol decanoate
T25487
Synonym: KD 16,KD-136,KD 136,Neoperidole,Haldol
Target: Others
Sertindole
T5858
Synonym: Lu 23-174
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Autophagy
Clothixamide
T13620
Synonym: Clotixamide
Target: Others
ORM-10921
T28267
Synonym: ORM10921,ORM 10921
Target: Adrenergic Receptor
Olanzapine N-Oxide
T28231
Synonym:
Target: Others
Dehydroaripiprazole
T10989
Synonym: OPC-14857,DM-14857
Target: 5-HT Receptor
NE-100 hydrochloride
T20797
Synonym: NE100 Hydrochloride,NE 100 HCl,NE 100 Hydrochloride,NE-100 Hydrochloride,NE-100 HCl
Target: Sigma receptor
Clopipazan
T68047
Synonym:
Target: Others
BD-1047 dihydrobromide
T1740
Synonym: BD1047.2HBr
Target: Sigma receptor
Ziprasidone hydrochloride
T0031L
Synonym: CP-88059 hydrochloride,CP-88059,Ziprasidone HCl
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Norepinephrine, Histamine Receptor
PD 144418 oxalate
T39211
Synonym:
Target: Sigma receptor
Promazine hydrochloride
T0766
Synonym: Romtiazin hydrochloride,Sinophenin hydrochloride
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, AChR
Carbidine
T23854
Synonym: Carbidine dihydrochloride,Karbidin,Carbidin,Karbidine
Target: Others
Tiaspirone hydrochloride
T24885L
Synonym: BMY-13859 hydrochloride,Tiaspirone hydrochloride(87691-91-6 Free base)
Target: Dopamine Receptor, 5-HT Receptor
Ziprasidone hydrochloride monohydrate
T0031
Synonym: CP 88059
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Norepinephrine, Histamine Receptor
AMI-193
T21855
Synonym: Espiramida,Spiramide
Target: Dopamine Receptor, 5-HT Receptor
Ziprasidone
T0031L2
Synonym: Geodon,Zeldox,CP-88059
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Norepinephrine, Histamine Receptor
SB 258585
T23318L
Synonym:
Target: 5-HT Receptor
Clozapine
T0455
Synonym: HF 1854,LX 100-129
Target: Dopamine Receptor, Adrenergic Receptor, AChR
Thioproperazine
T21368
Synonym: Megeptil,Sulfenazin,Cephalmin,Majeptyl,Vontil,Mazeptyl
Target:
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TargetMol